Contract award notice
Results of the procurement procedure
Section I: Contracting
entity
I.1) Name and addresses
UK Research and Innovation
Polaris House,North Star Avenue
SWINDON
SN21UH
UK
Contact person: Goods and Self Service
Telephone: +44 1793867005
E-mail: Coreservices@uksbs.co.uk
NUTS: UKK14
Internet address(es)
Main address: www.uksbs.co.uk
I.4) Type of the contracting authority
Other: Research
I.5) Main activity
Other: Research
Section II: Object
II.1) Scope of the procurement
II.1.1) Title
UK Research and Innovation - Oligonucleotide Synthesis and Nucleic Acid Sequencing Services Framework
Reference number: GSS23564
II.1.2) Main CPV code
73000000
II.1.3) Type of contract
Services
II.1.4) Short description
***This is an Award Notice, Not a Call for Competition****
This Framework has been established for the provision of UK Research and Innovation: Oligonucleotide Synthesis and Nucleic Acid Sequencing Services .
This Framework is being Established for a term of 3 years + 1 year
II.1.6) Information about lots
This contract is divided into lots:
Yes
II.1.7) Total value of the procurement
Value excluding VAT:
8 000 000.00
GBP
II.2) Description
Lot No: Sub Lot 1.1
II.2.1) Title
Sub Lot 1.1
II.2.2) Additional CPV code(s)
73000000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
Sub lot 1.1 - First Generation Nucleic Acid sequencing services
For the above sub lot, UKRI wish to put in place a framework for the purchase of a range of user selectable Nucleic Acid sequencing (Sanger/ ~800-1000 base pair read) services to be provided. This could include but is not limited to the following:
• Provide Phred 20 quality for as many nucleotides per sample as possible (min 800 bp or above for 5' 3' reads).
• Provide purification and sequencing of plasmids and PCR products in both 1.5 ml tubes and microtiter plates (must offer 96 well as a minimum).
• Provide purification and sequencing of plasmids supplied as Escherichia coli clones in both 1.5 ml tubes and microtiter plates (must offer 96 well as a minimum).
• Provide sequencing services using both primers synthesized by supplier and those with user provided primers.
• Provide Primer walking services in both double and single stranded DNA.
II.2.5) Award criteria
Quality criterion: Technical
/ Weighting: 10.00
Cost criterion: Commercial
/ Weighting: 90.00
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
Lot No: Sub Lot 1.2
II.2.1) Title
Sub Lot 1.2 - Second Generation Nucleic Acid Sequencing Services
II.2.2) Additional CPV code(s)
73000000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
Sub lot 1.2 - Second Generation Nucleic Acid sequencing services
For the above sub lot, UKRI wish to put in place a framework for the purchase of a range of Second Generation sequencing services from a range of samples and formats including tubes, microtiter plates, preparation & extractions services including from colonies and tissue samples.
A range of user selectable Nucleic Acid sequencing services are required that could include but not limited to:
• Ligation or sequencing by synthesis
• Pyrosequencing
• Dye sequencing
• Semiconductor based sequencing
• Provide sample pick-up or sample mailing/courier service as required.
• Provide purification and sequencing of samples supplied
• Offer suitable solutions to templates failing to give readable results
II.2.5) Award criteria
Quality criterion: Technical
/ Weighting: 10.00
Cost criterion: Commercial
/ Weighting: 90.00
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
Lot No: Sub Lot 1.3
II.2.1) Title
Sub Lot 1.3 - Third Generation Nucleic Acid Sequencing Services
II.2.2) Additional CPV code(s)
73000000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
Sub lot 1.3 - Third Generation Nucleic Acid sequencing services
For the above Sub Lot, UKRI wish to put in place a framework for the purchase of a range of Third generation sequencing services from a range of samples and formats including tubes, microtiter plates, preparation & extractions services including from colonies and tissue samples utilising novel or 'next generation technologies.
A range of user selectable Nucleic Acid sequencing services are required that could include but not limited to:
• PCR determination
• combinatorial probe-anchor synthesis (cPAS)
• fluorescently labelled antibody binding sequencing
• Single-molecule real-time (SMRT) sequencing
• zero-mode waveguide sequencing
• sequencing of DNA via Nano pore transition
II.2.5) Award criteria
Quality criterion: Technical
/ Weighting: 10.00
Cost criterion: Commercial
/ Weighting: 90.00
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
Lot No: Sub Lot 2.1
II.2.1) Title
Sub Lot 2.1 - Custom Gene fragment synthesis (sub 2000bp)
II.2.2) Additional CPV code(s)
24956000
73000000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
Sub lot 2.1 - Custom Gene fragment synthesis (sub 2000bp)
UKRI wish to put in place a framework for the purchase of a user selectable (via supplier engagement) range of Custom Gene Synthesis (sub 2000bp).
For the above sub lot, a range of user selectable additional services should be available (but are not mandatory). This could include but is not limited to the following:
• Genes produced with additional synthetic Nucleotides (AGTC + XY)
• Custom vector production
• Codon optimized sequences - all species
• Site-directed mutagenesis
• Bacterial, yeast, Baculovirus and mammalian gene expression services
• Complex sequence synthesis - GC rich, AT rich, complex repeats & hairpin structures and toxic sequences
II.2.5) Award criteria
Quality criterion: Technical
/ Weighting: 10.00
Cost criterion: Commercial
/ Weighting: 90.00
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
Lot No: Sub Lot 2.2
II.2.1) Title
Sub Lot 2.2 - Custom Gene synthesis (2001 - 3000bp)
II.2.2) Additional CPV code(s)
24956000
73000000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
UKRI wish to put in place a framework for the purchase of a user selectable (via supplier engagement) range of Custom Gene Synthesis (2001 - 3000bp).
For the above sub lot, a range of user selectable additional services should be available (but are not mandatory). This could include but is not limited to the following:
• Genes produced with additional synthetic Nucleotides (AGTC + XY)
• Custom vector production
• Codon optimized sequences - all species
• Site-directed mutagenesis
• Bacterial, yeast, Baculovirus and mammalian gene expression services
• Complex sequence synthesis - GC rich, AT rich, complex repeats & hairpin structures and toxic sequences
II.2.5) Award criteria
Quality criterion: Technical
/ Weighting: 10.00
Cost criterion: Commercial
/ Weighting: 90.00
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
Lot No: Sub Lot 2.3
II.2.1) Title
Sub Lot 2.3 - Custom Gene synthesis (3001-5000bp)
II.2.2) Additional CPV code(s)
24956000
73000000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
Sub Lot 2.3 - Custom Gene synthesis (3001-5000bp)
UKRI wish to put in place a framework for the purchase of a user selectable (via supplier engagement) range of Custom Gene Synthesis (3001 - 5000bp).
For the above sub lot, a range of user selectable additional services should be available (but are not mandatory). This could include but is not limited to the following:
• Genes produced with additional synthetic Nucleotides (AGTC + XY)
• Custom vector production
• Codon optimized sequences - all species
• Site-directed mutagenesis
• Bacterial, yeast, Baculovirus and mammalian gene expression services
• Complex sequence synthesis - GC rich, AT rich, complex repeats & hairpin structures and toxic sequences
II.2.5) Award criteria
Quality criterion: Technical
/ Weighting: 10.00
Cost criterion: Commercial
/ Weighting: 90.00
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
Lot No: Sub Lot 2.4
II.2.1) Title
Sub Lot 2.4 - Custom Gene synthesis (5001+ bp)
II.2.2) Additional CPV code(s)
24956000
73000000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
UKRI wish to put in place a framework for the purchase of a user selectable (via supplier engagement) range of Custom Gene Synthesis (5001 + bp).
For the above sub lot, a range of user selectable additional services should be available (but are not mandatory). This could include but is not limited to the following:
• Genes produced with additional synthetic Nucleotides (AGTC + XY)
• Custom vector production
• Codon optimized sequences - all species
• Site-directed mutagenesis
• Bacterial, yeast, Baculovirus and mammalian gene expression services
• Complex sequence synthesis - GC rich, AT rich, complex repeats & hairpin structures and toxic sequences
II.2.5) Award criteria
Quality criterion: Technical
/ Weighting: 10.00
Cost criterion: Technical
/ Weighting: 90.00
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
Lot No: Sub Lot 3.1
II.2.1) Title
Sub Lot 3.1 - Gene Specific DNA Methylation
II.2.2) Additional CPV code(s)
24956000
73000000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
Sub Lot 3.1 - Gene Specific DNA Methylation
UKRI wish to put in place a Framework for the purchase of a range of Gene Specific DNA Methylation services are required to include, but not limited to:
o Perform Bisulfite modification.
o Perform PCR reactions.
o Perform Pyrosequencing analysis.
II.2.5) Award criteria
Quality criterion: Technical
/ Weighting: 10.00
Cost criterion: Commercial
/ Weighting: 90.00
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
Lot No: Sub Lot 3.2
II.2.1) Title
Sub Lot 3.2 - Global DNA Methylation
II.2.2) Additional CPV code(s)
24956000
73000000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
Sub Lot 3.2 - Global DNA Methylation
UKRI wish to put in place a Framework for the purchase of a range of global DNA methylation services are required to include, but not limited to:
o LC MS DNA-methylation analysis.
o ELISA that enables the direct quantitation of genomic DNA methylation.
o PCR based methods e.g.; Alu and LINE1.
o Methylation sensitive restriction assays e.g.; luminometric methylation assay (LUMA).
II.2.5) Award criteria
Quality criterion: Technical
/ Weighting: 10.00
Cost criterion: Commercial
/ Weighting: 90.00
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
Lot No: Sub Lot 3.3
II.2.1) Title
Sub Lot 3.3 - Allele Quantification
II.2.2) Additional CPV code(s)
24956000
73000000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
Sub Lot 3.3 - Allele quantification
UKRI wish to put in place a Framework for the purchase of a range of Allele quantification services are required to include, but not limited to:
o SNP detection and quantification.
o Assay development for SNP detection and quantification from pooled DNA with a defined 100bp target region in murine DNA.
o Validation of the above assay.
o Sample testing if required for the above assay.
II.2.5) Award criteria
Quality criterion: Technical
/ Weighting: 10.00
Cost criterion: Commercial
/ Weighting: 90.00
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
Lot No: Sub Lot 4.1
II.2.1) Title
Sub Lot 4.1 - Synthesis of DNA Oligonucleotides
II.2.2) Additional CPV code(s)
24956000
73000000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
Sub Lot 4.1 - Synthesis of DNA oligonucleotides.
UKRI wish to put in place a framework for the purchase of a range of custom Oligonucleotide synthesis services including Custom DNA oligo's in tubes, plates and RNA/siRNA, to be user selectable via supplier engagement with a range of purification and modification options.
The production of custom user defined oligonucleotides in the following ranges are required (Inc. plates).
• 0.01UM bases standard
• 0.05UM bases standard
• 0.2UM bases standard
• 1.0UM bases standard
• 0.025 UM / 3OD
• Microtiter plates
II.2.5) Award criteria
Quality criterion: Technical
/ Weighting: 10.00
Cost criterion: Commercial
/ Weighting: 90.00
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
Lot No: Sub Lot 4.2
II.2.1) Title
Sub Lot 4.2 - Synthesis of Custom RNA Oligo's (both Single and double stranded RNA oligoes, siRNA) the supply of siRNA Libraries and the production of custom SiRNA Libraries
II.2.2) Additional CPV code(s)
24956000
73000000
II.2.3) Place of performance
NUTS code:
UK
II.2.4) Description of the procurement
Sub Lot 4.2 - Synthesis of Custom RNA oligo's (both Single and double stranded RNA oligoes, siRNA) the supply of siRNA Libraries and the production of custom SiRNA Libraries
UKRI wish to put in place a framework for the purchase of a range of custom Oligonucleotide synthesis services including Custom DNA oligo's in tubes, plates and RNA/siRNA, to be user selectable via supplier engagement with a range of purification and modification options.
The production of custom user defined oligonucleotides in the following ranges are required (Inc. plates).
• 0.01UM bases standard
• 0.05UM bases standard
• 0.2UM bases standard
• 1.0UM bases standard
• 0.025 UM / 3OD
• Microtiter plates
II.2.5) Award criteria
Quality criterion: Technical
/ Weighting: 10.00
Cost criterion: Commercial
/ Weighting: 90.00
II.2.11) Information about options
Options:
No
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds:
No
Section IV: Procedure
IV.1) Description
IV.1.1) Type of procedure
Open procedure
IV.1.3) Information about a framework agreement or a dynamic purchasing system
The procurement involves the establishment of a framework agreement
IV.1.8) Information about Government Procurement Agreement (GPA)
The procurement is covered by the Government Procurement Agreement:
Yes
IV.2) Administrative information
IV.2.1) Previous publication concerning this procedure
Notice number in the OJ S:
2023/S 000-027372
Section V: Award of contract
Lot No: Sub Lot 1.3
Contract No: GSS23564
A contract/lot is awarded:
Yes
V.2 Award of contract
V.2.1) Date of conclusion of the contract
01/05/2024
V.2.2) Information about tenders
Number of tenders received: 5
Number of tenders received by electronic means: 5
The contract has been awarded to a group of economic operators:
No
V.2.3) Name and address of the contractor
CeGat GmbH
HRB729958
Paul-Ehrlich-Straße 23
Tuebingen, Germany
D-72076
DE
NUTS: DE
The contractor is an SME:
No
V.2.4) Information on value of the contract/lot (excluding VAT)
Total value of the contract/lot:
: .01
GBP
V.2.5) Information about subcontracting
Section V: Award of contract
Lot No: Sub Lots 1.2 and 1.3
Contract No: GSS23564
A contract/lot is awarded:
Yes
V.2 Award of contract
V.2.1) Date of conclusion of the contract
01/05/2024
V.2.2) Information about tenders
Number of tenders received: 8
Number of tenders received by electronic means: 8
The contract has been awarded to a group of economic operators:
No
V.2.3) Name and address of the contractor
Edingburgh Genetics Limited
SC650426
Pentlands Science Park
Penicuick
EH26 0PZ
UK
NUTS: UKM
The contractor is an SME:
Yes
V.2.4) Information on value of the contract/lot (excluding VAT)
Total value of the contract/lot:
: .01
GBP
V.2.5) Information about subcontracting
Section V: Award of contract
Lot No: Sub Lots 1.1 / 2.1 / 2.2 / 2.3 / 2.4 / 4.1 / 4.2
Contract No: GSS23564
A contract/lot is awarded:
Yes
V.2 Award of contract
V.2.1) Date of conclusion of the contract
01/05/2024
V.2.2) Information about tenders
Number of tenders received: 35
Number of tenders received by electronic means: 35
The contract has been awarded to a group of economic operators:
No
V.2.3) Name and address of the contractor
Eurofins Genomics UK Ltd
03297407
i54 Business Park, Valiant Way
Wolverhampton
WV9 5GB
UK
NUTS: UK
The contractor is an SME:
No
V.2.4) Information on value of the contract/lot (excluding VAT)
Total value of the contract/lot:
: .01
GBP
V.2.5) Information about subcontracting
Section V: Award of contract
Lot No: Sub Lots 4.1 / 4.2
Contract No: GSS23564
A contract/lot is awarded:
Yes
V.2 Award of contract
V.2.1) Date of conclusion of the contract
01/05/2024
V.2.2) Information about tenders
Number of tenders received: 10
Number of tenders received by electronic means: 10
The contract has been awarded to a group of economic operators:
No
V.2.3) Name and address of the contractor
Eurogentec Ltd
(SC)139668
The Square Fawley
Southampton, Hampshire
SO45 1DD
UK
NUTS: UK
The contractor is an SME:
Yes
V.2.4) Information on value of the contract/lot (excluding VAT)
Total value of the contract/lot:
: .01
GBP
V.2.5) Information about subcontracting
Section V: Award of contract
Lot No: Sub Lots 1.1 / 1.3 / 2.1 / 2.2 / 2.3 / 2.4 / 3.3
Contract No: GSS23564
A contract/lot is awarded:
Yes
V.2 Award of contract
V.2.1) Date of conclusion of the contract
01/05/2024
V.2.2) Information about tenders
Number of tenders received: 31
Number of tenders received by electronic means: 31
The contract has been awarded to a group of economic operators:
No
V.2.3) Name and address of the contractor
Genewiz UK Ltd
09937828
Bullocks Lane, Hope End, Takeley
Essex
CM22 6TA
UK
NUTS: UK
The contractor is an SME:
No
V.2.4) Information on value of the contract/lot (excluding VAT)
Total value of the contract/lot:
: .01
GBP
V.2.5) Information about subcontracting
Section V: Award of contract
Lot No: Sub Lot 1.1
Contract No: GSS23564
A contract/lot is awarded:
Yes
V.2 Award of contract
V.2.1) Date of conclusion of the contract
01/05/2024
V.2.2) Information about tenders
Number of tenders received: 6
Number of tenders received by electronic means: 6
The contract has been awarded to a group of economic operators:
No
V.2.3) Name and address of the contractor
Macrogen Europe
NL04618247
Meibergdreef 57, 1105 BA
Amsterdam, The Netherlands
NL
NUTS: NL
The contractor is an SME:
No
V.2.4) Information on value of the contract/lot (excluding VAT)
Total value of the contract/lot:
: .01
GBP
V.2.5) Information about subcontracting
Section V: Award of contract
Lot No: Sub Lots 4.1 / 4.2
Contract No: GSS23564
A contract/lot is awarded:
Yes
V.2 Award of contract
V.2.1) Date of conclusion of the contract
01/05/2024
V.2.2) Information about tenders
Number of tenders received: 10
Number of tenders received by electronic means: 10
The contract has been awarded to a group of economic operators:
No
V.2.3) Name and address of the contractor
Merck Life Science UK Limited
00660457
The Old Brickyard, New Road
Gillingham, Dorset
SP8 4XT
UK
NUTS: UK
The contractor is an SME:
No
V.2.4) Information on value of the contract/lot (excluding VAT)
Total value of the contract/lot:
: .01
GBP
V.2.5) Information about subcontracting
Section V: Award of contract
Lot No: Sub Lots 1.1 / 1.2 / 1.3
Contract No: GSS23564
A contract/lot is awarded:
Yes
V.2 Award of contract
V.2.1) Date of conclusion of the contract
01/05/2024
V.2.2) Information about tenders
Number of tenders received: 14
Number of tenders received by electronic means: 14
The contract has been awarded to a group of economic operators:
No
V.2.3) Name and address of the contractor
Randox Laboratories Ltd
NI015738
55 The Diamond Road
Crumlin, Co Antrim
BT29 4QY
UK
NUTS: UK
The contractor is an SME:
No
V.2.4) Information on value of the contract/lot (excluding VAT)
Total value of the contract/lot:
: .01
GBP
V.2.5) Information about subcontracting
Section V: Award of contract
Lot No: Sub Lots 2.1 / 2.2 / 2.3
Contract No: GSS23564
A contract/lot is awarded:
Yes
V.2 Award of contract
V.2.1) Date of conclusion of the contract
01/05/2024
V.2.2) Information about tenders
Number of tenders received: 15
Number of tenders received by electronic means: 15
The contract has been awarded to a group of economic operators:
No
V.2.3) Name and address of the contractor
Twist Bioscience
333-231239
681 Gateway Blvd
South San Francisco, CA 94080
US
NUTS: US
The contractor is an SME:
No
V.2.4) Information on value of the contract/lot (excluding VAT)
Total value of the contract/lot:
: .01
GBP
V.2.5) Information about subcontracting
Section V: Award of contract
Lot No: Sub Lots 2.1 / 2.2 / 2.3 / 2.4 / 4.1 / 4.2
Contract No: GSS23564
A contract/lot is awarded:
Yes
V.2 Award of contract
V.2.1) Date of conclusion of the contract
01/05/2024
V.2.2) Information about tenders
Number of tenders received: 29
Number of tenders received by electronic means: 29
The contract has been awarded to a group of economic operators:
No
V.2.3) Name and address of the contractor
Life Technologies Limited
SC083107
3 Fountain Drive, Inchinnan Business Park
Paisley
PA4 9RF
UK
NUTS: UK
The contractor is an SME:
No
V.2.4) Information on value of the contract/lot (excluding VAT)
Initial estimated total value of the contract/lot:
Total value of the contract/lot:
: .01
GBP
V.2.5) Information about subcontracting
Section V: Award of contract
Lot No: Sub Lots 1.1 / 1.2 / 1.3
Contract No: GSS23564
A contract/lot is awarded:
Yes
V.2 Award of contract
V.2.1) Date of conclusion of the contract
01/05/2024
V.2.2) Information about tenders
Number of tenders received: 14
Number of tenders received by electronic means: 14
The contract has been awarded to a group of economic operators:
No
V.2.3) Name and address of the contractor
Source Bioscience UK Ltd
04078501
1 Orchard Place, Nottingham Business
Nottinghamshire
NG8 6PX
UK
NUTS: UK
The contractor is an SME:
Yes
V.2.4) Information on value of the contract/lot (excluding VAT)
Total value of the contract/lot:
: .01
GBP
V.2.5) Information about subcontracting
Section V: Award of contract
Lot No: 2.1 / 2.2 / 2.3 / 2.4 / 4.1 / 4.2
Contract No: GSS23564
A contract/lot is awarded:
Yes
V.2 Award of contract
V.2.1) Date of conclusion of the contract
01/05/2024
V.2.2) Information about tenders
Number of tenders received: 29
Number of tenders received by electronic means: 29
The contract has been awarded to a group of economic operators:
No
V.2.3) Name and address of the contractor
IDT DNA
9869050
London City Point, 1 Ropemaker Street
London
EC2Y 9HT
UK
NUTS: UK
The contractor is an SME:
No
V.2.4) Information on value of the contract/lot (excluding VAT)
Total value of the contract/lot:
: .01
GBP
V.2.5) Information about subcontracting
Section VI: Complementary information
VI.3) Additional information
This Framework Agreement has been let on a 3 year + 1 year basis
VI.4) Procedures for review
VI.4.1) Review body
UK Shared Business Services Ltd
Polaris House, North Star Avenue
Swindon
SN2 1FF
UK
E-mail: policy@uksbs.co.uk
Internet address(es)
URL: www.uksbs.co.uk
VI.5) Date of dispatch of this notice
25/06/2024